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Modulation of the Kv1.3 Potassium Channel by Receptor Tyrosine Kinases

The voltage-dependent potassium channel, Kv1.3, is modulated by the epidermal growth factor receptor (EGFr) and the insulin receptor tyrosine kinases. When the EGFr and Kv1.3 are coexpressed in HEK 293 cells, acute treatment of the cells with EGF during a patch recording can suppress the Kv1.3 curre...

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Autores principales: Bowlby, Mark R., Fadool, Debra A., Holmes, Todd C., Levitan, Irwin B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229388/
https://ncbi.nlm.nih.gov/pubmed/9348331
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