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Modulation of potassium channel gating by external divalent cations

We have examined the actions of Zn2+ ions on Shaker K channels. We found that low (100 microM) concentrations of Zn2+ produced a substantial (approximately three-fold) slowing of the kinetics of macroscopic activation and inactivation. Channel deactivation was much less affected. These results were...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229231/
https://ncbi.nlm.nih.gov/pubmed/7836936
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