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Evidence for a direct interaction between internal tetra-alkylammonium cations and the inactivation gate of cardiac sodium channels
The effects of internal tetrabutylammonium (TBA) and tetrapentylammonium (TPeA) were studied on human cardiac sodium channels (hH1) expressed in a mammalian tsA201 cell line. Outward currents were measured at positive voltages using a reversed Na gradient. TBA and TPeA cause a concentration-dependen...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229220/ https://ncbi.nlm.nih.gov/pubmed/7807060 |
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