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Functional characterization of B lymphocytes generated in vitro from embryonic stem cells

To study molecular events involved in B lymphocyte development and V(D)J rearrangement, we have established an efficient system for the differentiation of embryonic stem (ES) cells into mature Ig-secreting B lymphocytes. Here, we show that B lineage cells generated in vitro from ES cells are functio...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Cho, Sarah K., Webber, Travis D., Carlyle, James R., Nakano, Toru, Lewis, Susanna M., Zúñiga-Pflücker, Juan Carlos
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9797
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