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A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors

Vertebrate rod photoreceptors in the dark maintain an inward current across the outer segment membrane. The photoresponse results from a light-induced suppression of this dark current. The light-regulated current is not sensitive to either tetrodotoxin or amiloride, potent blockers of Na+ channels....

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1987
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228879/
https://ncbi.nlm.nih.gov/pubmed/2826642
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