Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression

BACKGROUND: NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have been associated with Crohn disease, a human chronic inflammatory bowel disease....

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Autors principals: Rosenstiel, Philip, Huse, Klaus, Franke, Andre, Hampe, Jochen, Reichwald, Kathrin, Platzer, Cornelia, Roberts, Roland G, Mathew, Christopher G, Platzer, Matthias, Schreiber, Stefan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228316/
https://ncbi.nlm.nih.gov/pubmed/18096043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-472
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