Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas.

Chromosome 6q has been shown to be one of the most frequent sites for allelic loss in human breast cancer. The mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) gene, which maps to chromosome 6q26-27, functions in the activation of TGF-beta1, a potent growth inhibitor for most cell t...

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Hlavní autoři: Chappell, S. A., Walsh, T., Walker, R. A., Shaw, J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228213/
https://ncbi.nlm.nih.gov/pubmed/9413941
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