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Prognostic value of loss of heterozygosity at BRCA2 in human breast carcinoma.

To confirm several recent studies pointing to loss of heterozygosity (LOH) at BRCA2 as a prognostic factor in sporadic breast cancer, we examined this genetic alteration in a large series of human primary breast tumours for which long-term patient outcomes were known. LOH at BRCA2 correlated only wi...

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Autors principals: Bièche, I., Noguès, C., Rivoilan, S., Khodja, A., Latil, A., Lidereau, R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228174/
https://ncbi.nlm.nih.gov/pubmed/9400936
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