Reduced expression of the ICE-related protease CPP32 is associated with radiation-induced cisplatin resistance in HeLa cells.

Low-dose fractionated gamma-irradiation (three cycles of 5 x 2 Gy) induced cisplatin resistance in HeLa cells. The drug resistance was modest (Rf of about 2) and stable, similar to that found previously in murine cells after irradiation. In the drug-resistant HeLa-C3 cells, flow cytometric analysis...

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Bibliographic Details
Main Authors: Eichholtz-Wirth, H., Stoetzer, O., Marx, K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228159/
https://ncbi.nlm.nih.gov/pubmed/9374378
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