Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy.

The NAD(P)H quinone oxidoreductase (NQO1:EC 1.6.99.2) is an important biotransformation enzyme system that is also known to metabolize important novel chemotherapeutic compounds. The gene that codes for this enzyme has recently been found to be polymorphic in humans. Here, we describe the ethnic dis...

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Hlavní autoři: Kelsey, K. T., Ross, D., Traver, R. D., Christiani, D. C., Zuo, Z. F., Spitz, M. R., Wang, M., Xu, X., Lee, B. K., Schwartz, B. S., Wiencke, J. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228056/
https://ncbi.nlm.nih.gov/pubmed/9328142
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