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Factors affecting aminolaevulinic acid-induced generation of protoporphyrin IX.

Photodynamic therapy (PDT) may cause tumour cell destruction by direct toxicity or by inducing cellular hypoxia as a result of microcirculatory shutdown. Aminolaevulinic acid (ALA) causes cellular accumulation of protoporphyrin IX (PPIX) in cells exposed to it in excess. PPIX can be used as a photos...

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Autori principali: Wyld, L., Burn, J. L., Reed, M. W., Brown, N. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228050/
https://ncbi.nlm.nih.gov/pubmed/9310234
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