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Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP.

There is a pressing need to reduce the time and cost of developing new cytotoxic agents and to accurately identify clinically active agents at an early stage. In this study, the differential staining cytotoxicity (DiSC) assay was used to assess the efficacy of the novel antitumour cAMP analogue, 8-c...

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Autori principali: Bosanquet, A. G., Burlton, A. R., Bell, P. B., Harris, A. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227987/
https://ncbi.nlm.nih.gov/pubmed/9275029
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