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Immunization of HLA-A*0201 and/or HLA-DPβ1*04 Patients with Metastatic Melanoma Using Epitopes from the NY-ESO-1 Antigen

HLA class I-restricted peptides are often used in peptide vaccine regimens. There is strong evidence that many of these peptides can generate specific CD8(+) T-cell responses in vivo; however, only occasional objective clinical responses have been reported. To test whether provision of “help” would...

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Autors principals: Khong, Hung T., Yang, James C., Topalian, Suzanne L., Sherry, Richard M., Mavroukakis, Sharon A., White, Donald E., Rosenberg, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227905/
https://ncbi.nlm.nih.gov/pubmed/15534491
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