Human eosinophils regulate human lung- and skin-derived fibroblast properties in vitro: A role for transforming growth factor β (TGF-β)

Eosinophils have been associated with fibrosis. To investigate their direct role in fibrosis, human peripheral blood eosinophil sonicate was added to human lung or dermal fibroblasts, and proliferation ([(3)H]thymidine) and collagen synthesis ([(3)H]proline) were evaluated. Proliferation was enhance...

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Hauptverfasser: Levi-Schaffer, Francesca, Garbuzenko, Ekaterina, Rubin, Ann, Reich, Reuven, Pickholz, Dalia, Gillery, Philippe, Emonard, Herve, Nagler, Arnon, Maquart, Francois A. Xavier
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22266/
https://ncbi.nlm.nih.gov/pubmed/10449750
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