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Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

We have studied the effects of the proteolytic enzyme Pronase on the membrane currents of voltage-clamped squid axons. Internal perfusion of the axons with Pronase rather selectively destroys inactivation of the Na conductance (g (Na)). At the level of a single channel, Pronase probably acts in an a...

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Autores principales: Armstrong, Clay M., Bezanilla, Francisco, Rojas, Eduardo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1973
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2226121/
https://ncbi.nlm.nih.gov/pubmed/4755846
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