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Tetrodotoxin Desensitization in Aggregates of Embryonic Chick Heart Cells

Spontaneous beating of heart-cell aggregates from 4-day chick embryos was initially blocked by 10(-5) g/ml tetrodotoxin (TTX). With continued exposure to the drug, the fraction of blocked aggregates decreased from about 80% at 15 min to about 25% at 2–3 h, at which time, beating aggregates had becom...

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Bibliographic Details
Main Authors: McDonald, Terence F., Sachs, Howard G., DeHaan, Robert L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1973
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2226116/
https://ncbi.nlm.nih.gov/pubmed/4730668
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