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Regulation of Type 1 Inositol 1,4,5-Trisphosphate–gated Calcium Channels by InsP(3 )and Calcium : Simulation of Single Channel Kinetics Based on Ligand Binding and Electrophysiological Analysis
Cytosolic calcium acts as both a coagonist and an inhibitor of the type 1 inositol 1,4,5-trisphosphate (InsP(3))–gated Ca channel, resulting in a bell-shaped Ca dependence of channel activity (Bezprozvanny, I., J. Watras, and B.E. Ehrlich. 1991. Nature. 351:751–754; Finch, E.A., T.J. Turner, and S.M...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2225610/ https://ncbi.nlm.nih.gov/pubmed/10352034 |
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