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Potassium-dependent Changes in the Conformation of the Kv2.1 Potassium Channel Pore

The voltage-gated K(+) channel, Kv2.1, conducts Na(+) in the absence of K(+). External tetraethylammonium (TEA(o)) blocks K(+) currents through Kv2.1 with an IC(50) of 5 mM, but is completely without effect in the absence of K(+). TEA(o) block can be titrated back upon addition of low [K(+)]. This s...

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Sonraí Bibleagrafaíochta
Main Authors: Immke, David, Wood, Michael, Kiss, Laszlo, Korn, Stephen J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 1999
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225608/
https://ncbi.nlm.nih.gov/pubmed/10352033
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