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Sleep-Stabilizing Effects of E-6199, Compared to Zopiclone, Zolpidem and THIP in Mice
Gamma aminobutyric acid (GABA)A receptor modulators constitute the majority of clinically used sedative-hypnotics. These compounds have the capacity to initiate and maintain sleep, but decrease REM sleep and delta activity within NREM sleep. In order to avoid such sleep adverse effects, the developm...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Associated Professional Sleep Societies, LLC
2008
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2225576/ https://ncbi.nlm.nih.gov/pubmed/18274274 |
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