Neonatal lipopolysaccharide exposure exacerbates stress-induced suppression of LH pulse frequency in adulthood

Early life exposure to immunological challenge has programming effects on the adult hypothalamo-pituitary-adrenocortical (HPA) axis stress responsivity and stress is known to suppress GnRH pulse generator activity, especially LH pulses. We investigated the effects of neonatal exposure to endotoxin o...

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Main Authors: Li, X.F., Kinsey-Jones, J.S., Knox, A.M.I., Wu, X. Q., Tahsinsoy, D., Brain, S.D., Lightman, S.L., O'Byrne, K.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225523/
https://ncbi.nlm.nih.gov/pubmed/17872370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0710
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