Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

BACKGROUND: CCR5-restricted (R5) human immunodeficiency virus type 1 (HIV-1) variants cause CD4+ T-cell loss in the majority of individuals who progress to AIDS, but mechanisms underlying the pathogenicity of R5 strains are poorly understood. To better understand envelope glycoprotein (Env) determin...

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Hlavní autoři: Sterjovski, Jasminka, Churchill, Melissa J, Ellett, Anne, Gray, Lachlan R, Roche, Michael J, Dunfee, Rebecca L, Purcell, Damian FJ, Saksena, Nitin, Wang, Bin, Sonza, Secondo, Wesselingh, Steven L, Karlsson, Ingrid, Fenyo, Eva-Maria, Gabuzda, Dana, Cunningham, Anthony L, Gorry, Paul R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225424/
https://ncbi.nlm.nih.gov/pubmed/18076768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-89
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