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Crystallization and preliminary X-ray analysis of a native human tRNA synthetase whose allelic variants are associated with Charcot–Marie–Tooth disease

Glycyl-tRNA synthetase (GlyRS) is one of a group of enzymes that catalyze the synthesis of aminoacyl-tRNAs for translation. Mutations of human and mouse GlyRSs are causally associated with Charcot–Marie–Tooth disease, the most common genetic disorder of the peripheral nervous system. As the first st...

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Hlavní autoři: Xie, Wei, Schimmel, Paul, Yang, Xiang-Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225372/
https://ncbi.nlm.nih.gov/pubmed/17142907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106046434
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