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Purification and crystallization of the human EF-hand tumour suppressor protein S100A2

S100A2 is a Ca(2+)-binding EF-hand protein that is mainly localized in the nucleus. There, it acts as a tumour suppressor by binding and activating p53. Wild-type S100A2 and a S100A2 variant lacking cysteines have been purified. CD spectroscopy showed that there are no changes in secondary-structure...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Koch, Michael, Diez, Joachim, Fritz, Günter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: International Union of Crystallography 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225223/
https://ncbi.nlm.nih.gov/pubmed/17077493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106039881
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