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The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa

The blue chloroform-soluble bacterial metabolite pyocyanin (1-hydroxy-5-­methyl-phenazine) contributes to the survival and virulence of Pseudomonas aeruginosa, an important Gram-negative opportunistic pathogen of humans and animals. Little is known about the two enzymes, designated PhzM and PhzS, th...

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Detalhes bibliográficos
Main Authors: Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dmitri V., Blankenfeldt, Wulf
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225181/
https://ncbi.nlm.nih.gov/pubmed/17012792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106034464
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