Regions on adenylyl cyclase that are necessary for inhibition of activity by βγ and G(iα) subunits of heterotrimeric G proteins

The two large cytoplasmic domains (C1 and C2) of adenylyl cyclases (AC), when expressed separately and mixed together, reconstitute enzyme activity that can be regulated by various modulators. Therefore, we have used the C1 or its C1a subdomain and C2 regions from type I AC (ACI) and type V AC (ACV)...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Wittpoth, Claus, Scholich, Klaus, Yigzaw, Yinges, Stringfield, Teresa M., Patel, Tarun B.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1999
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22246/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9551
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