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The 3′ Untranslated Region of Sindbis Virus Represses Deadenylation of Viral Transcripts in Mosquito and Mammalian Cells

The positive-sense transcripts of Sindbis virus (SINV) resemble cellular mRNAs in that they possess a 5′ cap and a 3′ poly(A) tail. It is likely, therefore, that SINV RNAs must successfully overcome the cytoplasmic mRNA decay machinery of the cell in order to establish an efficient, productive infec...

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Autors principals: Garneau, Nicole L., Sokoloski, Kevin J., Opyrchal, Mateusz, Neff, C. Preston, Wilusz, Carol J., Wilusz, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224598/
https://ncbi.nlm.nih.gov/pubmed/17977976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01205-07
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