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The U95 Protein of Human Herpesvirus 6B Interacts with Human GRIM-19: Silencing of U95 Expression Reduces Viral Load and Abrogates Loss of Mitochondrial Membrane Potential

To better understand the pathogenesis of human herpesvirus 6 (HHV-6), it is important to elucidate the functional aspects of immediate-early (IE) genes at the initial phase of the infection. To study the functional role of the HHV-6B IE gene encoding U95, we generated a U95-Myc fusion protein and sc...

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Bibliografiske detaljer
Main Authors: Yeo, W. M., Isegawa, Yuji, Chow, Vincent T. K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224593/
https://ncbi.nlm.nih.gov/pubmed/17928352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-07
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