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Subtype-Specific Conformational Differences within the V3 Region of Subtype B and Subtype C Human Immunodeficiency Virus Type 1 Env Proteins

The V3 region of the human immunodeficiency virus type 1 gp120 Env protein is a key domain in Env due to its role in interacting with the coreceptors CCR5 and CXCR4. We examined potential subtype-specific V3 region differences by comparing patterns of amino acid variability and probing for subtype-s...

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Detalles Bibliográficos
Main Authors: Patel, Milloni B., Hoffman, Noah G., Swanstrom, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224581/
https://ncbi.nlm.nih.gov/pubmed/18003735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01444-07
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