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Integrin α(V)β(3) Binds to the RGD Motif of Glycoprotein B of Kaposi's Sarcoma-Associated Herpesvirus and Functions as an RGD-Dependent Entry Receptor

Kaposi's sarcoma-associated herpesvirus (KSHV) envelope-associated glycoprotein B (gB) is involved in the initial steps of binding to host cells during KSHV infection. gB contains an RGD motif reported to bind the integrin α(3)β(1) during virus entry. Although the ligand specificity of α(3)β(1)...

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Bibliographic Details
Main Authors: Garrigues, H. Jacques, Rubinchikova, Yelena E., DiPersio, C. Michael, Rose, Timothy M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224453/
https://ncbi.nlm.nih.gov/pubmed/18045938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01673-07
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