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Flock House Virus Induces Apoptosis by Depletion of Drosophila Inhibitor-of-Apoptosis Protein DIAP1

The molecular mechanisms by which RNA viruses induce apoptosis and apoptosis-associated pathology are not fully understood. Here we show that flock house virus (FHV), one of the simplest RNA viruses (family, Nodaviridae), induces robust apoptosis of permissive Drosophila Line-1 (DL-1) cells. To defi...

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Detalhes bibliográficos
Main Authors: Settles, Erik W., Friesen, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224432/
https://ncbi.nlm.nih.gov/pubmed/17989181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01941-07
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