Adaptation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins to New World Monkey Receptors

Human immunodeficiency virus type 1 (HIV-1) infection encounters an early block in the cells of New World monkeys because the CD4 receptor does not efficiently support HIV-1 entry. We adapted HIV-1(NL4-3) and HIV-1(KB9), two HIV-1 variants with different envelope glycoproteins, to replicate efficien...

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Bibliographic Details
Main Authors: Pacheco, Beatriz, Basmaciogullari, Stephane, LaBonte, Jason A., Xiang, Shi-Hua, Sodroski, Joseph
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224371/
https://ncbi.nlm.nih.gov/pubmed/17959679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01299-07
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