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An alcohol binding site on the neural cell adhesion molecule L1
Prenatal ethanol exposure causes fetal alcohol spectrum disorders (FASD) in part by disrupting the neural cell adhesion molecule L1. L1 gene mutations cause neuropathological abnormalities similar to those of FASD. Ethanol and 1-butanol inhibit L1-mediated cell–cell adhesion (L1 adhesion), whereas 1...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224219/ https://ncbi.nlm.nih.gov/pubmed/18165316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707815105 |
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