An alcohol binding site on the neural cell adhesion molecule L1

Prenatal ethanol exposure causes fetal alcohol spectrum disorders (FASD) in part by disrupting the neural cell adhesion molecule L1. L1 gene mutations cause neuropathological abnormalities similar to those of FASD. Ethanol and 1-butanol inhibit L1-mediated cell–cell adhesion (L1 adhesion), whereas 1...

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Bibliografiska uppgifter
Huvudupphovsmän: Arevalo, Enrique, Shanmugasundararaj, Sivananthaperumal, Wilkemeyer, Michael F., Dou, Xiaowei, Chen, Suzhen, Charness, Michael E., Miller, Keith W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224219/
https://ncbi.nlm.nih.gov/pubmed/18165316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707815105
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