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Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer

Chromophore-assisted light inactivation is a promising technique to inactivate selected proteins with high spatial and temporal resolution in living cells, but its use has been limited because of the lack of a methodology to prevent nonspecific photodamage in the cell owing to reactive oxygen specie...

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Bibliografiske detaljer
Main Authors: Yogo, Takatoshi, Urano, Yasuteru, Mizushima, Akiko, Sunahara, Hisato, Inoue, Takanari, Hirose, Kenzo, Iino, Masamitsu, Kikuchi, Kazuya, Nagano, Tetsuo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224201/
https://ncbi.nlm.nih.gov/pubmed/18172220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611717105
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