The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: Implications for a dual role as a primer recognition factor and processivity clamp

The accessory subunit of the heterodimeric mtDNA polymerase (polγ) from Drosophila embryos is required to maintain the structural integrity or catalytic efficiency of the holoenzyme. cDNAs for the accessory subunit from Drosophila, man, mouse, and rat have been identified, and comparative sequence a...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Fan, Li, Sanschagrin, Paul C., Kaguni, Laurie S., Kuhn, Leslie A.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1999
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9527
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