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ACTION OF MITOCHONDRIAL DNAASE I IN DESTROYING THE CAPACITY OF ISOLATED CELL NUCLEI TO FORM GELS

1. DNA prepared from non-gelable rat liver nuclei isolated in the presence of disrupted mitochondria at pH 6.0, has been compared with DNA obtained from gelable nuclei isolated at pH 4.0. The DNA of the non-gelable nuclei is partially depolymerized relative to the DNA of the gelable nuclei. 2. It ha...

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Détails bibliographiques
Auteurs principaux: Dounce, Alexander L., O'Connell, Marguerite P., Monty, Kenneth J.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1957
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224124/
https://ncbi.nlm.nih.gov/pubmed/13475382
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