Mutated Response Regulator graR Is Responsible for Phenotypic Conversion of Staphylococcus aureus from Heterogeneous Vancomycin-Intermediate Resistance to Vancomycin-Intermediate Resistance

Multistep genetic alteration is required for methicillin-resistant Staphylococcus aureus (MRSA) to achieve the level of vancomycin resistance of vancomycin-intermediate S. aureus (VISA). In the progression of vancomycin resistance, strains with heterogeneous vancomycin resistance, designated hetero-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Neoh, Hui-min, Cui, Longzhu, Yuzawa, Harumi, Takeuchi, Fumihiko, Matsuo, Miki, Hiramatsu, Keiichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223914/
https://ncbi.nlm.nih.gov/pubmed/17954695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00534-07
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