Subinhibitory Concentrations of Azithromycin Decrease Nontypeable Haemophilus influenzae Biofilm Formation and Diminish Established Biofilms

Nontypeable Haemophilus influenzae (NTHi) commonly causes otitis media, chronic bronchitis in emphysema, and early airway infections in cystic fibrosis. Long-term, low-dose azithromycin has been shown to improve clinical outcomes in chronic lung diseases, although the mechanism of action remains unc...

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Bibliografiske detaljer
Main Authors: Starner, Timothy D., Shrout, Joshua D., Parsek, Matthew R., Appelbaum, Peter C., Kim, GunHee
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223912/
https://ncbi.nlm.nih.gov/pubmed/17954687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00607-07
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