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Substitutions at Auxiliary Operator O3 Enhance Repression by Nitrate-Responsive Regulator NarL at Synthetic lac Control Regions in Escherichia coli K-12

We constructed monocopy lac operon control regions in which the operators O1-lac and O3-lac were replaced by NarL and NarP binding sites from the nirB or napF operon control regions. The results support the hypothesis that DNA-bound dimers of phospho-NarL can participate in higher-order cooperative...

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Detalhes bibliográficos
Main Authors: Stewart, Valley, Bledsoe, Peggy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223736/
https://ncbi.nlm.nih.gov/pubmed/17965164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01431-07
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