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The location of acidic fibroblast growth factor in the breast is dependent on the activity of proteases present in breast cancer tissue.

Acidic fibroblast growth factor (FGF1) and two of its receptors, FGFR1 and FGFR4, were localized in cryostat sections of normal, benign and malignant human breast tissue by immunohistochemistry. Without pretreatment, FGF1 staining was mainly seen in normal epithelial cells. However, polymerase chain...

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Autori principali: Coope, R. C., Browne, P. J., Yiangou, C., Bansal, G. S., Walters, J., Groome, N., Shousha, S., Johnston, C. L., Coombes, R. C., Gomm, J. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223526/
https://ncbi.nlm.nih.gov/pubmed/9184178
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