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Listeria monocytogenes Desensitizes Immune Cells to Subsequent Ca(2+) Signaling via Listeriolysin O-Induced Depletion of Intracellular Ca(2+) Stores

Listeriolysin O (LLO), the pore-forming toxin of Listeria monocytogenes, is a prototype of the cholesterol-dependent cytolysins (CDCs) secreted by several pathogenic and nonpathogenic gram-positive bacteria. In addition to mediating the escape of the bacterium into the cytosol, this toxin is general...

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Detalhes bibliográficos
Main Authors: Gekara, Nelson O., Groebe, Lothar, Viegas, Nuno, Weiss, Siegfried
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223449/
https://ncbi.nlm.nih.gov/pubmed/18056478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00622-07
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