Epigenetic and Phenotypic Consequences of a Truncation Disrupting the Imprinted Domain on Distal Mouse Chromosome 7

The distal end of mouse chromosome 7 (Chr 7) contains a large cluster of imprinted genes. In this region two cis-acting imprinting centers, IC1 (H19 DMR) and IC2 (KvDMR1), define proximal and distal subdomains, respectively. To assess the functional independence of IC1 in the context of Chr 7, we de...

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Bibliographic Details
Main Authors: Oh, Rosemary, Ho, Rita, Mar, Lynn, Gertsenstein, Marina, Paderova, Jana, Hsien, John, Squire, Jeremy A., Higgins, Michael J., Nagy, Andras, Lefebvre, Louis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223404/
https://ncbi.nlm.nih.gov/pubmed/18039841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01019-07
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