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The MLE Subunit of the Drosophila MSL Complex Uses Its ATPase Activity for Dosage Compensation and Its Helicase Activity for Targeting

In Drosophila, dosage compensation—the equalization of most X-linked gene products between XY males and XX females—is mediated by the MSL complex that preferentially associates with numerous sites on the X chromosome in somatic cells of males, but not of females. The complex consists of a noncoding...

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Autors principals: Morra, Rosa, Smith, Edwin R., Yokoyama, Ruth, Lucchesi, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223400/
https://ncbi.nlm.nih.gov/pubmed/18039854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00995-07
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