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Gcn5p Plays an Important Role in Centromere Kinetochore Function in Budding Yeast

We report that the histone acetyltransferase Gcn5p is involved in cell cycle progression, whereas its absence induces several mitotic defects, including inefficient nuclear division, chromosome loss, delayed G(2) progression, and spindle elongation. The fidelity of chromosome segregation is finely r...

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Main Authors: Vernarecci, Stefano, Ornaghi, Prisca, Bâgu, AnaCristina, Cundari, Enrico, Ballario, Paola, Filetici, Patrizia
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223381/
https://ncbi.nlm.nih.gov/pubmed/18039853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01366-07
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