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Prevention of Skin Tumorigenesis and Impairment of Epidermal Cell Proliferation by Targeted Aquaporin-3 Gene Disruption

Aquaporin-3 (AQP3) is a water/glycerol-transporting protein expressed strongly at the plasma membranes of basal epidermal cells in skin. We found that human skin squamous cell carcinoma strongly overexpresses AQP3. A novel role for AQP3 in skin tumorigenesis was discovered using mice with targeted A...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hara-Chikuma, Mariko, Verkman, A. S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223314/
https://ncbi.nlm.nih.gov/pubmed/17967887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01482-07
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