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Nicotinamide Uncouples Hormone-Dependent Chromatin Remodeling from Transcription Complex Assembly

Sirtuins, homologs of the yeast SIR2 family, are protein deacetylases that require nicotinamide adenosine dinucleotide as cofactor. To determine whether the sirtuin family of deacetylases is involved in progesterone receptor (PR)-mediated transcription, the effect of sirtuin inhibitor, nicotinamide...

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Библиографические подробности
Главные авторы: Aoyagi, Sayura, Archer, Trevor K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223307/
https://ncbi.nlm.nih.gov/pubmed/17954562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01158-07
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