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The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection
The antiviral factor tripartite interaction motif 5α (Trim5α) restricts a broad range of retroviruses in a species-specific manner. Although human Trim5α is unable to block HIV-1 infection in human cells, a modest inhibition of HIV-1 replication has been reported. Recently two polymorphisms in the T...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222955/ https://ncbi.nlm.nih.gov/pubmed/18248091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040018 |
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