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Notch Signalling Synchronizes the Zebrafish Segmentation Clock but Is Not Needed To Create Somite Boundaries
Somite segmentation depends on a gene expression oscillator or clock in the posterior presomitic mesoderm (PSM) and on read-out machinery in the anterior PSM to convert the pattern of clock phases into a somite pattern. Notch pathway mutations disrupt somitogenesis, and previous studies have suggest...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222926/ https://ncbi.nlm.nih.gov/pubmed/18248098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0040015 |
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