ER Stress-Mediated Apoptosis in a New Mouse Model of Osteogenesis imperfecta

Osteogenesis imperfecta is an inherited disorder characterized by increased bone fragility, fractures, and osteoporosis, and most cases are caused by mutations affecting the type I collagen genes. Here, we describe a new mouse model for Osteogenesis imperfecta termed Aga2 (abnormal gait 2) that was...

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Detalhes bibliográficos
Main Authors: Lisse, Thomas S, Thiele, Frank, Fuchs, Helmut, Hans, Wolfgang, Przemeck, Gerhard K. H, Abe, Koichiro, Rathkolb, Birgit, Quintanilla-Martinez, Leticia, Hoelzlwimmer, Gabriele, Helfrich, Miep, Wolf, Eckhard, Ralston, Stuart H, de Angelis, Martin Hrabé
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222924/
https://ncbi.nlm.nih.gov/pubmed/18248096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0040007
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