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Rapid and Direct Effects of pH on Connexins Revealed by the Connexin46 Hemichannel Preparation

pH is a potent modulator of gap junction (GJ) mediated cell–cell communication. Mechanisms proposed for closure of GJ channels by acidification include direct actions of H(+) on GJ proteins and indirect actions mediated by soluble intermediates. Here we report on the effects of acidification on conn...

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Autors principals: Brady Trexler, E., Bukauskas, Feliksas F., Bennett, Michael V.L., Bargiello, Thaddeus A., Verselis, Vytas K.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222913/
https://ncbi.nlm.nih.gov/pubmed/10228184
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