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Mechanism of Allosteric Modulation of Rod Cyclic Nucleotide–gated Channels

The cyclic nucleotide–gated (CNG) channel of retinal rod photoreceptor cells is an allosteric protein whose activation is coupled to a conformational change in the ligand-binding site. The bovine rod CNG channel can be activated by a number of different agonists, including cGMP, cIMP, and cAMP. Thes...

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Autori principali: Sunderman, Elizabeth R., Zagotta, William N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222912/
https://ncbi.nlm.nih.gov/pubmed/10228178
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